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KMID : 0388220090160020144
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Journal of the Korean Rheumatism Association
2009 Volume.16 No. 2 p.144 ~ p.149
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A Case of Adult Acute Myeloid Leukemia Presenting with Musculoskeletal Manifestations
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Kim Hyun-Dong
Hwang Ji-Sun
Cho Yun-Jeong
Han Na-Mi
Jung Kyu-Young
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Abstract
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Leukemia is a heterogenous group of neoplasms that arise from the malignant transformation of hematopoietic cells. The usual presentation is one of lethargy, pallor, fever, purpura, bleeding, etc, and all this is secondary to a decrease in the production of normal blood components. However, leukemia often manifests with musculoskeletal symptoms without a systemic presentation. Musculoskeletal symptoms that precede the recognition of leukemia are much less frequent in adults as compared to those in children, and this causes diagnostic confusion and a delayed diagnosis. We describe here a case of adult acute myeloid leukemia in which pain and weakness of the limbs were the main manifestations and these were suspected as being symptoms of musculoskeletal disease.
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KEYWORD
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Leukemia, Musculoskeletal manifestations
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